Chordotonal organs
نویسندگان
چکیده
only human. Very recently, a senior research associate in my lab shared his experience of accidentally spilling a hazardous chemical on the floor and the small change he will make to contain such spills more safely in the future. I am grateful that he used his experience to help us all work smarter and safer. These two stories have been about lab mistakes, the last one will be about remembering to bring your whole game to your research. Software design and computer programming was my entry point into research as a high school student, skills that I further developed at University. Foolishly, I decided as a PhD student that I wanted to be a biologist, not a programmer and intentionally let my skills atrophy. Now, I am scrambling to get back in shape and update my skills so that our research need not be limited to the tools others build.
منابع مشابه
The structure and function of auditory chordotonal organs in insects.
Insects are capable of detecting a broad range of acoustic signals transmitted through air, water, or solids. Auditory sensory organs are morphologically diverse with respect to their body location, accessory structures, and number of sensilla, but remarkably uniform in that most are innervated by chordotonal organs. Chordotonal organs are structurally complex Type I mechanoreceptors that are d...
متن کاملEB1 is essential during Drosophila development and plays a crucial role in the integrity of chordotonal mechanosensory organs.
EB1 is a conserved microtubule plus end tracking protein considered to play crucial roles in microtubule organization and the interaction of microtubules with the cell cortex. Despite intense studies carried out in yeast and cultured cells, the role of EB1 in multicellular systems remains to be elucidated. Here, we describe the first genetic study of EB1 in developing animals. We show that one ...
متن کاملRole of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors.
The Drosophila gene atonal encodes a basic helix-loop-helix protein similar to those encoded by the proneural genes of the achaete-scute complex (AS-C). The AS-C are required in the Drosophila PNS for the selection of neural precursors of external sense organs. We have isolated mutants of atonal, which reveal that this gene encodes the proneural gene for chordotonal organs and photoreceptors. I...
متن کاملThe insecticide pymetrozine selectively affects chordotonal mechanoreceptors.
Pymetrozine is a neuroactive insecticide but its site of action in the nervous system is unknown. Based on previous studies of symptoms in the locust, the feedback loop controlling the femur-tibia joint of the middle leg was chosen to examine possible targets of the insecticide. The femoral chordotonal organ, which monitors joint position and movement, turned out to be the primary site of pymet...
متن کاملThe specificity of proneural genes in determining Drosophila sense organ identity
The proneural genes (atonal and the genes of the achaete-scute complex (AS-C)) are required for the selection of sense organ precursors. They also endow these precursors with sense organ subtype information. In most of the ectoderm, atonal is required for precursors of chordotonal sense organs, whereas AS-C are required for those of most external sense organs, such as bristles. To address the q...
متن کاملRequirement for EGF receptor signalling in neural recruitment during formation of Drosophila chordotonal sense organ clusters
BACKGROUND Drosophila proneural genes act in the process of selecting neural precursors from undifferentiated ectoderm. The proneural gene atonal is required for the development of precursors of both chordotonal organs (stretch receptors) and photoreceptors. Although these types of sensory element are dissimilar in structure and function, they both occur as organized arrays of neurons. Previous...
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ورودعنوان ژورنال:
- Current Biology
دوره 23 شماره
صفحات -
تاریخ انتشار 2013